Products
TRIP13 antibody
- Product Name
- TRIP13 antibody
- Catalogue No.
- FNab08997
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- thyroid hormone receptor interactor 13
- Alternative Names
- 16E1 BP antibody, 16E1BP antibody, PCH2 antibody, TR interacting protein 13 antibody, TRIP 13 antibody, TRIP13 antibody
- UniProt ID
- Q15645
- Observed MW
- 49 kDa
Application
- Tested Applications
- ELISA, WB, IP, IHC
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08997(TRIP13 antibody) at dilution of 1:400
IP Result of anti-TRIP13 (IP: FNab08997, 3ug; Detection: FNab08997 1:400) with mouse testis tissue lysate 3000ug.
Immunohistochemistry of paraffin-embedded mouse testis tissue slide using FNab08997 (TRIP13 antibody) at dilution of 1:200
- Background
- Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).
